What is Perlane®?

Perlane, approved by the FDA in May of this year, is a "mid-dermal" hyaluronic acid filler product. As a sister product to Restylane, Perlane is designed for more pronounced facial folds and wrinkles such as those on the sides of the mouth.

Perlane is injected into the deep dermis to superficial layer of the subcutis to add volume to restore surface contour in facial wrinkles and folds. Perlane corrections maintain volume augmentation for about six months before natural product degradation begins to lessen the effects.

How is Perlane different from Restylane?

Both Perlane and Restylane are composed of hyaluronic acid. The primary difference between Restylane and Perlane is that the hyaluronic acid gel particles in Perlane are larger than those found in Restylane. This gives Perlane additional ability to lift and fill the areas of injection that require a denser formulation. Perlane and Restylane are perfect complements to one another.

How do Perlane and Restylane work?

Perlane® is injected into the skin to smooth away wrinkles and folds. Perlane®’s water-loving nature attracts and binds water molecules to help maintain volume.

Perlane® is composed of hyaluronic acid, a natural substance that already exists in the body. The hyaluronic acid in Perlane® is a crystal clear gel that is chemically cross-linked (the long chemical strands are tied together) to delay breakdown by skin enzymes. Perlane® is non-animal-based and free from animal protein. This quality prevents disease transmission. Allergy pre-testing is not necessary. Also distinct from other hyaluronic acid dermal fillers, Restylane and Perlane are minimally cross-linked, making them similar to the natural hyaluronic acid found in the body.